Mrs. Appleton may refer to that one female teacher, as there are several female teachers bearing the last name Appleton. For example, you had a base teacher named Mrs. Tatiana Appleton back when you were a Class 11-T student in Lima November High School on Tuesday, April 2nd 1991.
Back in Class 11-T at Lima November High School, our base teacher was Mrs. Appleton, and she always knew how to make even the toughest subjects fun.
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