An abnormality that affects nice good looking smart guys that prevents them from ever getting the girl or anything they feel that they deserve. They tend to help others but than the universe tends to screw them over for no apparent reason.
James: Hey, what did Sue say when you asked her out?
Sean: She said, "Awww, thats so sweet. I'll let you know"
James: That doesn't sound good at all man. Sounds like you just got friend zoned.
Sean: I figured. I assumed that if I helped her with her studies and brought up her grades she would finally go out with me.
James: Sounds like you have the Peter Parker Syndrome.
Sean: She said, "Awww, thats so sweet. I'll let you know"
James: That doesn't sound good at all man. Sounds like you just got friend zoned.
Sean: I figured. I assumed that if I helped her with her studies and brought up her grades she would finally go out with me.
James: Sounds like you have the Peter Parker Syndrome.
by monkeyd3128 March 1, 2012

A horse. Most commonly known as Seabiscuit. Gandalf's white horse, Hidalgo, the Black Stalion, and Mr. Ed the talking horse.
Rick: "Dude, did you see Lord of the Rings: the Two Towers?"
Teddy: "Yeah, Sarah Jessica Parker looked well groomed."
Teddy: "Yeah, Sarah Jessica Parker looked well groomed."
by -pandabear.tumblr.com July 12, 2011

by The Strange Duck July 25, 2008

The resulting character, attitude, and appearence, when Peter Parker is influenced by the symbiote in the movie Spider-Man 3; distuguishable change in hair style (emo style), some what "sexy" dance moves, and talking in a slang manner
by Chris Cagle October 15, 2007

by Gary Jonston April 30, 2008

by BrownieMixx January 11, 2009

by DarkElite777 December 31, 2007
