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Loose Caboose 

used to refer to a person with a loose anus. Usually happens when said person has participated in copious amounts of anal sex.
"Sally said we have to stop doing anal because she is starting to get a loose caboose."
Loose Caboose by Anal Jim April 25, 2011
Caboose is one of the Blue Team's soldiers from Red vs Blue. He is the only one who knows how to drive Shiela, although, in an act of a team-killing F**k-tard, killed Church.

It was later found out that Church killed Church, although Caboose was still known as a team-killing f**k-tard.

Caboose was also responsible for discovering a talking bomb named Andy, constantly sucking up to Church, and naming an alien Fluffy, the alien that only loves.
"So that makes you... a gay robot." -Caboose
Caboose by Xarrin April 21, 2006
the rookie of the blue team, also, the funniest character in the entire series
Tucker: whats that huge thing?
Caboose: Thats church.
church: He means the ship caboose!
caboose by alec4231 April 9, 2008

deuce caboose 

The deuce caboose is a quite humorus term refering to the toilet and defacating, dropping a deuce.
"Dude, that mexican food went right through me! When I got home I headed straight for the deuce caboose and dropped one, wait I mean two!
deuce caboose by Dustin Crew November 23, 2007

Caboose Slag 

Any female that frequents the scumfuck bar The Loose Caboose (The Loose Asshole) in Lafayette, Louisiana.
Typically a college-aged female, but not necesarily college student, who listens to nu metal, has tribal tattoo(s), still wears the same Jncos bought from Gadzooks in 97', and has a myriad of issues that require her to take depakote or some other crazy person medication.
Caboose Slag by POND SCUM October 1, 2004

caboose on the loose

someone who does not follow the crowd
While walking down the street, Allison noticed a caboose on the loose named Sam who was wearing shoes on her hands