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The Black Plague

A mutated form of "Bieber Fever", over One Million people were infected 3 weeks after the outbreak. Symptoms include confusion in front-back seat identification, driving at 13, an insatiable need for bowls of cereal, and random black guys.
The whole school had been infected with The Black Plague. The word "Friday" rang through the halls.
The Black Plague by Skilljoy April 15, 2011
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The Uncommon Plague 

The Uncommon Plague is like the Common Plague, except worse. There is no cure. Once you get the Uncommon Plague, you're basically fucked. You cough up more bad memes, you slowly start losing your memes. You can get it by going onto Tumblr. frequently.
Guy 1: Hey, I heard Guy 2 got the Uncommon Plague.
Guy 3: Yeah, there is no cure, he might lose his memes forever.
Guy 1: Oh jeez, rip Guy 2.

The Windows Plague 

A plague that seems to have infected millions of people around the world, it's one known effect is lulling people into the false belief that PC's are better than Mac's. It may sound silly but is an increasing problem having enormous effects on todays society. The one known cure to this malicious disease is an iPod.
Dave: I like my PC cos it runs the best operating system in the world Windows on it.

Harry: Hah looks like you've still got The Windows Plague, here check this out, (hands Dave an iPod)

Dave: Wha-? This is genius! Must of been made by Microsoft.

Harry: -_-; *sigh*
The Windows Plague by An On E Mouse February 17, 2008

avoid like the fucking plague 

The plague was a deadly disease. If you got infected by the bacteria, you would die. Obviously you don't want to die. So if you avoid something like you would avoid the plague the plague, you really, really try to avoid it.
That man I avoid like the fucking plague.

the Black Plauge 

in walks a throwed nigga, and everyone says "yo somebody get the black plauge out a heyre"
the Black Plauge by Jamofo August 23, 2003

The New Plague

The New Plague is another term for aids theat GWAR(the best death-metal band ever) first used in a song entitled The New Plague to tell how he got aids
"Im just a person, and ive got The New Plague;
I dont know how i got this way;
I drank some whiskey, went and got laid;
now im a person jus a person with aids!"
-by GWAR, the best death-metal band ever!!!(probobly the best band overall biatch!)
The New Plague by oderus orungus December 14, 2008

The Black Plague

an illness where one listens to "Friday" by Rebecca Black and the song is forever looped in their mind. Highly contagious
Guy 1 :"Man, I've got a bad case of the black plague"
Rebecca Black: "THIS WORLD SHALL BE MINE!!!"
The Black Plague by sahgdzhsjc April 12, 2011