- Being or becoming very bored with an over-bearing and/or boring topic of discussion or conversation.
- Losing interest in a trivial discussion or conversation with friends or co-workers.
"I was standing talking to Kevin at the water cooler, and all of the sudden he said "...just never mind, I've lost interest...." and he walked away! WTF?"
"Brian loses interest in topics of discussion very easily, he's always saying "...I've lost interest...." and walks away.
A phrase uttered in the drive thru at a fast food restaurant in regards to whether or not one should pay the extra money for cheese on their burger. Usually happens on a first "date", but not exclusive to thus. Also virtually guarantees no second date.
man in drive thru: "We'll have two hamburgers, two small fries, and two medium diet cokes"