Person 1: Do you want any mayo de noche with your fries?
Person 2: Did you take your grandpa's pills again?
Person 2: Did you take your grandpa's pills again?
by Shrek Fan May 5, 2023

Mayo is slang for the word Mayonnaise, a.k.a. the greatest food to ever exist, if you do not eat this, you have problems
John: Holy Crap I love mayo!
Sam: How can you love mayo, it sucks.
John: WTF is wrong with you Sam, are you retarded.
Sam: How can you love mayo, it sucks.
John: WTF is wrong with you Sam, are you retarded.
by Get egged on March 13, 2020

An upstate New York term used mainly by Hispanic thug boys or frats to describe a female as being mid or just average quality in looks.
Male 1: Ayo Pablo you see that shorty over there?
Make 2: Yeah homie she a cinco de mayo if I ever saw one
Male 1: you right homes she a middie
Make 2: Yeah homie she a cinco de mayo if I ever saw one
Male 1: you right homes she a middie
by The New York hillbilly February 2, 2023

when a cat grabs a bottle of heinz mayo, they learn the definition of the world, and only speaks
"you i am
a mayo"
"you i am
a mayo"
by Assistacat February 3, 2021

(Somewhat derogatory) A white person, implies a nefarious intent behind the white race. Mayo relates to the white color of the condiment and its popularity among whites, and devil implies a sinister intent behind either an individual or whites as a whole. Also see “bleach demon.” May be used in an argument with a white person
by Thepissmaster373 June 25, 2025

by WhiteFax June 23, 2023
