A "Handsome Andy" is a pressed ham with a twist. First, one presses his bare buttocks against the window of a moving car. Second, he flips the bird to another car. Third, he places "the bird" (i.e., his swear finger) into his anus, thereby achieving a "Handsome Andy."
Carl: That trucker is driving like a maniac. Should I give him a pressed ham?
Susan: Why don't you be a man for once, Carl, and give him a Handsome Andy?
Susan: Why don't you be a man for once, Carl, and give him a Handsome Andy?
by Ramon187 December 15, 2010

Person 1: *Calls indian scammer without realizing*
Person 1: Hello, I went to this weird website and it said to call this number
Scammer: Yes, yes, yes, go to this website and install this andy wirus sostware
Person 1: Hello, I went to this weird website and it said to call this number
Scammer: Yes, yes, yes, go to this website and install this andy wirus sostware
by ChrisIsFun November 17, 2019

by deewtee January 31, 2010

by ParanoidAndroid71 October 8, 2006

by Undead0scar May 27, 2017

by AntisocialWeeb August 24, 2018

A cast member on SNL who was made popular by his digital shorts such as Dick in a Box, Lazy Sunday, Jizz in my Pants, I'm on a Boat, Like a Boss, and the new sequel to Dick in a Box, Motherlover.
He was also the star in the movie Hot Rod, and had a role in the movie I Love You, Man.
He is one third of the comedy troup The Lonely Island with his childhood friends Akiva and Jorma.
He was also the star in the movie Hot Rod, and had a role in the movie I Love You, Man.
He is one third of the comedy troup The Lonely Island with his childhood friends Akiva and Jorma.
by lkdfjasdlfja May 16, 2009
