1. Reflex exclamation of pain, discomfort or physical shock.

2. (In response to the above) An expression of empathy.

Synonyms: ow, ouch, argh
"Oof, that hurt!"

"Oof, I feel your pain, man!"
by DashW0 May 16, 2010
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when you get roasted so hard that you don't now what to say.
mean girl:ur crocs are not even that sparkely
Mean girls friends:YEET
Me:oof jessica I didn't think you'd AtTAcK me like that...oof
by finnayeetis January 14, 2019
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Retarded Roblox meme that somehow got popular.
Dies in COD*
9-yr-old: oof
by dogwiz November 28, 2017
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The act of a gamer expressing pain, or a gamer's reaction to something unfortunate.
(Katherine falls off of her chair) John: OOF!
by BIG OOFS March 18, 2019
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The word used when you either don’t care what someone is saying, or are completely antisocial and have no other way to contribute, add to, or end a conversation.
Person 1: Did you hear about what happened to Brian? He is in the Hospital

Person 2: Oof
by ManguyManguyguyguy February 19, 2020
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when someone tells you some wack shit and you dont know how to answer
friends: my boyfriend got me pregnant and dipped
me: oof
by marina_ March 14, 2019
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a sound made when in discomfort or when wind is blown out of your system. Also popular in Roblox.
He hit Robert and Robert said oof or *killed my roblox player* OOF
by karlg77 June 8, 2018
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