by r.i.p.mj July 7, 2009

Someone who is a slut,whore, tramp, or turns trics. Referring mostly to females. She openly appears as a slut and is very forward in the way she approaches a male. She mostly performs sexual deeds for males and brags about it.
(origin: Philly particularly in the North East area)
(origin: Philly particularly in the North East area)
by UD Girl 116 August 12, 2009

by banana rammer April 27, 2011

a krunck non-sleepin,but hell yea be eatin who likes to twist tha pizzy fa shizzy my nizzy. Tha fool cleans betta than Mr. Clean. Ya got a new best friend cause they speak nothin but tha truth in tha end. Maybe bad and u may get sad, but while ur tweekin u aint nothing but glad. And you see them still seekin....and thats the definition of tweekin.
That Tweeker Rox!!
by Queen Tweeker January 25, 2004

by rock-a-jock-a-man December 13, 2008

a tweeker is someone acting like a retard. constantly flipping out over stupid shit. just plain fucking annoying.
The lady that works at the register was being a tweeker because the credit card was too close to the register.
by used4life September 2, 2005
