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To abruptly, and rudely, cut someone off as they are speaking -particularly when the speaker (who is addressing a large audience) is at the climax of their speech.

In its purest form - the interruption is intended to berate, discredit, embarrass and utterly humiliate the speaker.
Poor Taylor Swift got "Kanye'd" at the Video Music Awards!

Dan was proudly explaining to his staff how his new system would enhance the company's output when Penelope "Kanye'd" him by saying, "Your system is a piece of shit!"
Kanye by Who Woulda Thought September 15, 2009
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Fuck you Kanye!
Kanye by HYT65 September 14, 2009
one person acting like a piece of shit to another person
Making that little boy cry by stealing his ice cream was such a Kanye move.
Kanye by OffendedMama September 15, 2009
A tool bag, one who espaecially likes to take the limelight
also like a mormon
Kid - Why'd he just start blurting out the answers, they were wrong?
other kid - Oh he's just a kanye
Kanye by kanye-hater September 16, 2009
Acting like a jackass or doche in front of a group of people.
Kanye by Money00 September 21, 2009
a style of dress: pretty boy with "extra" accessories (large belt buckle, bookbag with no books, stooper-big watch)
Look at this guy, pullin a kanye: does he have to have the belt buckle with a pocket protector on it?
Kanye by mr wordsamillion! December 23, 2005
The act of interrupting and/ or stealing the metaphorical spotlight from another through the act of the offender putting his/ herself out in the open with the intention of making a valid point.This usually ends in the unintentional making an ass of the offender self.
"Dude, you totally Kanyed me by correcting my grammar during the debate. But it's ok, 'cause now everyone thinks you're a total ASS"
Kanye by captain plantain September 15, 2009