SIS is an acronym popularized by the Canadian music artist Peaches in her song "Fuck The Pain Away" and it means "Stay in School".
Person 1: Remember the teachings of Peaches: "S-I-S, IUD, Stay in School 'cause it's the best"
Pesron 2: I love Peaches and, you know what, school is really the best!
Pesron 2: I love Peaches and, you know what, school is really the best!
by Max the Mad Cat May 26, 2024
Get the S-I-Smug. by anonymous December 13, 2020
Get the Smug. HahahahahahahahahahahahahahahahahahahaHahahahahahahahahahahahahahahahahahahahahahahahahahahaha Hahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahaha A funni word
by JoemamaligmaballscAndicedick November 1, 2021
Get the S eggsmug. by Big Daddy Bobo April 16, 2022
Get the Holding up 4’smug. by Soap bar May 31, 2022
Get the Throwing up 4,smug. 
