A cup of what's up

promethazine mixed with sprite.

I had a long day at work, I can really use a cup of what's up to relax me.

by TheRig December 4, 2012

Say what up to John

The act of taking a huge dab to become really high

Hey man, what do you say we go say what up to John after church?

by Dr. Anita Cain N’Degochello September 21, 2018

What up

When you are too gay for the homies

Yo what up gang

by Carterb13 August 11, 2022

What’s up brother

A common saying/ greeting in the madden gaming community. Popularized by a streamer named Sketch. It is customary to raise you index finger while using this saying/ greeting.

Person 1: hey

Person 2: what’s up brother.

by PEEPEEHands04 May 6, 2024

what up ninja

A youtube channle made by a stoner for stoners

"Yo you see that new what up ninja video that stoner is crazyyy"

by Big daddy665 July 20, 2021

what up

What Up is a phrase commonly used by Barney Stinson, usually heard at the end of a comically appropriate sexual comment, often accompanied by a high five. Its style varies from time to time as do most of Barney's catchphrases, being either high-pitched or low-pitched, oddly pronounced or even not verbally said.

Open bar for the guys, open casket for the ladies, what up!

by hakunama tata July 21, 2019

What’s up brother

When you see someone you say what’s up brother to see what reaction they have
For example:Tuesday Tuesday, speical teams special plays special players, what’s up brother, no reaction

Girl:1/What’s up brother
Boy1/speical teams special plays special players

by Qwertygenalpha April 28, 2024