Jenny: oh my god! Keefe is so hot!
Susan: he's not real jen
Jenny: SHUT UP SUSAN THAT'S WHY NOBODY LIKES YOU , YOU FAT BITCH
by I AM SARCASM July 17, 2020
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A handsome individual who rejected his humanity and in turn got all the hot babes.
Brian: I know you want to be a Keefe, but that's only a dream. Sometimes you just got to let some dreams go.
Kevin: Shut up Brian, you're just jealous that I'm getting closer to becoming a Keefe.
by CornyRonnie February 20, 2021
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The crystals that fall off really good marijuana.
After I shook that hydro, I had about a gram of killer keefe
by Pilaf May 30, 2008
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a more subtle substitute for "fucked, screwed over or jipped"

1. the position to be in that is a result of a problem or bad situation that seems impossible to solve/get out of
1. "Dude, I think Dennis KEEFED his coworkers real good yesterday."
by Hotelbutel March 31, 2016
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Gaelic meaning handsome, noble, gentle, lovable.
"Ach! You're so Keefe, I could just pinch your cheeks: both sets!"
by Elan J February 5, 2010
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The most potent form of marijuana; marijuana that contains crystals.
by Judah February 17, 2005
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A very hot guy from Keeper of the Lost Cities who has perfect hair and is perfect for Sophie. Team Foster-Keefe all the way!
"Keefe is really fucking hot."

"You did NOT just insult the hair." -Keefe himself.
by Queen011CatFury February 11, 2023
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