Sticky upie

Sticking up in all directions...such as hair when you wake up.

My hair is all sticky upie.

by Peaches9112 June 19, 2017

UPI

Universal Prostate Institute.

A made-up institution to serve as an excuse when somebody asks where you graduated.

George: Do you have a degree in computer science?

Johnson: Oh yeah, I graduated at UPI...

by Bin_NoGoutHavinAss_Chang January 12, 2022

UPI

Universal Place Identifier

The UPI for Queretaro is queretaro

by blabloz September 19, 2019

Upis

To shoot a gun at a minor that doesn't know spanish and has two feet with 6 six toes

Oh look an Upis I need to shoot it

by Upis February 04, 2023

UPI

Unidentified party injury

dude...where'd you get that huge bruise. I don't recall. It's a upi from Saturday night.

by rawr kitty December 31, 2016