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Homie with an extra chromie 

Person with Down Syndrome, due to the fact the condition is caused by a person being born with 47 chromosomes instead of 46.
That guy with Down Syndrome is my Homie with an extra chromie.
Related Words

Homie discount 

A homie discount is 50% off of the price. A true homie discount is on the house.
Homie 1: Let me get that homie discount.

Homie 2: Alright bruh I'll take 50 off.

Homie 1: Come on man I've been a good homie to you.

Homie 2: Bruh you have been go ahead and take it.
Homie discount by Stud6969 July 7, 2016

Homie Glide 

When one heterosexual man lubes up another heterosexual mans butt cheeks then continues to hump it in a titty fucking fashion. There is no penetration of the anus therefor is not gay.
"Yo, Arthur, I'm bored and like women, should we homie glide to pass the time"
Homie Glide by anhyzerdfpr March 15, 2010

Homie Rover 

A ghetto fabulous Range Rover or Land Rover. Has a customer paint job with one bright color such as orange and a secondary dark color such as black.
Hey Scott, did you see the car Emmanuel picked his kid up in. He totally bought a Homie Rover, drive slow homie!
Homie Rover by CircusBear December 16, 2017

homie cuddle 

“hey man you tryna come over and homie cuddle?

“what’s that bro”

“just cuddling, but homies
homie cuddle by elloitsella December 18, 2019

homie dawg 

A slang word for friend. Used when trying to sound cool.
Hey, homie dawg, you going to the movies tonight?
No, it's alright. We're homie dawgs, we're cool.
homie dawg by Fred Kowalski September 25, 2005