Suddenly getting really kick-ass and unbeatable in Smash Bros. due to some unknown source of adrenaline or many hours of practice.
Dom: Dude, I'm totally tweaking out!
Luke: SHUT UP, you guys!
by Amelia Q November 15, 2004
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To tweak out is to loose control of your body, fall to the ground, and start making strange motions and noises(Not really passing out, just loose control with conciseness). Normally happens when large amounts of marijuana are in the body, the person attempts to stand and get a huge head rush, thus falls over. This can be strange seeing, but don't worry, pot can't kill ya :)
Woah dude, head rush... He mumbled as he stumbled and crashed on the book shelf. We all laughed as he tweak out on the ground.
by ismellit June 3, 2007
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its like saying, be cool before i go crazy ts
*somebody does some stupid shit*, "aye, cuzzo lock in foe i tweak out'
by iihearttnunu._ April 12, 2022
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be mine before i go berserks on yo ass / shooting yo shot
aye yo carmen , lock in foe i tweak out😎😩”
by nonchalantkeii April 29, 2022
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