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Someone or something that drives people crazy (v.q. someone with a loose screw).
Don't listen to him! He obviously has his screwdriver stuck in lefty-loosey, he's just gonna drive you crazy!
by BQ Atkin December 26, 2022
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A phrase used to describe a woman with huge hanging boobs.
Woman 1: Dude, did you see those F's on the loose?
Woman 2: Yea, they were huge.
Woman 1: It was like two watermelons were hanging from her chest.
Woman 2: But even with those things she was ugly as hell.
Woman 1: Yea, totally.
by Andrew the Grouch December 17, 2013
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loose screw

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crazy; silly; mad; lunatic; loony; insane
"She's a little loose screw for talking like that to us."
by Pawnstar December 18, 2012
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One single cigarette often sold on street corners and city public transportation. Usually sold by bums and drug dealers.
Riding the Red Line train in Chicago, you will always come across someone selling loose squares, Frooties, the Sun Times, and pepper spray.
by Shae December 11, 2004
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Loose Skrews

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The Loose Skrews are a punk rock band that was founded in Atlanta.They been doing there own unique brand of punk/Oi since 2003. They also started a large fan following called "The Brew Crew".

Members:
Rotger Rotgut- Vocals
J.B.- Bass
Clayton- Lead Guitar
Hooper- Rhythm Guitar
Gabe- Drums

Albums include:
More Than A Few
Have Another Brew,
Born To Lose,
For Those Hearts True.
The Loose Skrews kick ass!!!
by tunaking June 28, 2009
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Loose Stool

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Damn dude i have loose stool. I just shat on myself.
by devo12665 February 17, 2006
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loose shooting

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Recklessly ejaculating in a girl you really don't like, possible causing an unwanted pregnancy.
Person One: This cat is crying cause he got (insert name of one night stand woman here) pregnant.

Person Two: Good for his ass he shouldn't have been loose shooting.
by AJames June 11, 2006
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