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It's an acronym for Down For Whatever. Applies to a myriad of situations, but is extensively used by a crew in Massachusetts to describe a woman who is basically down for doing anything, including unusual or what some would deem to be "risque" sex acts. It also has non-sexual uses, which can be seen below, indicating a lack of preference.
Yo, that chick in Amsterdam was crazy B! She was absolutely DFW.

Dude, I'm cool with that Steak & Cheese sub, in fact, I'm DFW today.

Ever heard that song "DFW"?
DFW by The Phenom December 31, 2008
Related Words
Down F or Whateva
Person #1: "Are you DFW tonight to hit-up Downtown Dallas???"
DFW by M0n1k3R February 23, 2014
Down For Whatever
Hey is that hot beezy DFW?
DFW by dasterdlydegree April 22, 2011
Down for whatever.
Dave; hey what do you wanna do tonight? ;)
Trisha; i dunno i'm DFW
DFW by Kymbella0318 February 3, 2014
1: Dumb Fucking Whore
2: Down for Whatever
"Hey michael, you wanna go to the movies? Yeah, I'm DFW!"
DFW by Heather James July 6, 2005
DFW has the TrAAin not the "TrAAm" get it right! ****TrAAin!!!****... A friendly big airport that always has delays during which you can ride around on AA's TrAAin and kill some time until it breaks down on you like it always does and your stuck there for 20 minutes killing more time. Sometimes, the TrAAin just stops working before you even get on it :( in which case prepare to be directed by angry fat people to the moving walkways.
DFW is replacing their world-class TrAAin from 1912 with the new SkyLink/SkyTrain whatever in July 2005.
DFW by Food11 July 6, 2005