Down syndrome

Someone with an extra chromosome

He liking his balls i think he has Down syndrome

by Illegal border hopper April 21, 2022

FaZe Down syndrome

FaZe Down syndrome is when a fan of the Call of Duty league franchise "Atlanta FaZe" becomes so obsessed with the team that all logic flies out the window

Symptoms include:
Agreeing with everything a faze player says
Making awful excuses about why faze lost a game (eg. "It was Rigged!")
Arguing with anyone on twitter who says faze isn't the best

That guy over there thinks simp is greater than Scump he obviously has FaZe Down Syndrome

by Realistic faze fab January 21, 2023

Down Syndrome

when you have all the chromosones

Yea Nathan have down syndrome

by boudaciousslayqueen420 June 9, 2022

Yes in a down syndrome voice

When someone says yes but like they are missing chromosomes

"YEEEEEESSSSSSS"
"oh no hes doing yes in a down syndrome voice"

by WildWillez December 13, 2020

Down Syndrome Ass

A large and disproportionate butt

Yo Trayvon, have you seen Taylor's ass lately. That girl is walking around with a down syndrome ass without even knowing it.

by White Boi Brain January 16, 2024

down syndrome ass

"Down syndrome ass" is a colloquial term used to describe a buttocks that appears larger or differently shaped than typical. It's often characterized by a notable prominence or awkwardness in its form, resembling the appearance associated with Down syndrome, a genetic disorder. This term is not medically or scientifically recognized and can be considered offensive due to its derogatory nature.

"Yo, check out Shawty over there with that Down syndrome ass, it's like two basketballs stuffed in her jeans, no lie."

"Yeah, she got that Down syndrome ass, it's like she's carrying a whole extra load back there, making heads turn on the block."

Bro, her booty's like 'bam!' – Down syndrome ass, making the hood go wild, you feel me?"

by Brained February 7, 2024

down syndrome nigel

the retarded kid at in class who always had snot running into his mouth

down syndrome nigel breaks stupidity world record

by mrs tosser August 6, 2025