Big-P Disease

When you become EXTREMELY sexy and charming with the voice and face of an angel. You can catch this disease by comming in contact with Pete Lepore.

" god damn, i wish i had the Big-P Disease because im an ugly shit. "

by Pimpin' Pete December 28, 2005

Brett Favre's Disease

A douchebag who doesn't know when to quit.

Derived from Lou Gerig's disease

In 1939, when Gehrig sat for the first time in years after a streak of 2130 starts, the Detroit crowd gave him a standing ovation as he sat slumped in the dugout, his eyes welling with tears.

Favre's starting streak ending unlike Gehrig's after returning from countless retirements, to an awful season performance, a sexual harassment charge, and venom from the state that once loved him.

Favre was a douchbag to the very end:

“I heard people say ‘Hate for the streak to end like this,’” Favre said. “End like what? It’s been a great run.”

Only in your mind Brett, only in your mind.

Why is Dave at the club? Isn't he like, 45 years old? Everyone thinks he's a joke out there dancing like that.

I know dude, but be a little bit understanding. He's got a bad case of Brett Favre's Disease.

After Tom sent those pictures to Jenny after her constant ignoring of his text messages he realized a horrible truth; He had Brett Favre's Disease.

by lawlawlaw December 15, 2010

mad clown disease

An affliction which causes a speech-related abnormality only when saying the word "unfortunately." Whereas a normal person would say "un-for-chun-it-lee," a person in the later stages of mad clown disease will say "un-for-toon-ut-lee," much like a homosexual penguin. It's passed from person to person (or penguin) through Paris Hilton. Mad clown disease was first discovered by Dr. Al K. Seltzer in Pietermaritzburg, South Africa. You know, "South" Africa? Vast strides have been made in the fight against mad clown disease. As of yet, no cure is forthcoming, and the disease is viciously contagious. Currently, the method we are using to study the disease is spending time in the Paris Hilton (not the hotel). What? It's research!

Oh no, another outbreak of mad clown disease! Euthanize all penguins and Hilton sisters! Stay away from their orifices!

by Guoderaj March 18, 2008

Celiac's Disease

An autoimmune disorder that affects upwards of 17 people, with 98% cases occurring in or near affluent, well-to-do, upper-class suburban areas. Causes sufferers to experience symptoms such as:

•whining,

•annoying the people around you who work for a living,
•cramping,

•rash,

•saying "I can't have gluten" until people want to punch you for it
•Hallucinations of having an actual disease
•Shopping at Trader Joe's, unnecessarily
•shifting political views towards the left

Celiac's has never been documented in white-collar or homeless populations, and is mainly self-diagnosed, therefore, very little is known about it.

Tommy: "I bought some donuts!"
Kate: "Do they have gluten? Abby can't have them if they have gluten, she has Celiac's Disease."
Tommy: "The fuck she does."

by yalpdrow December 19, 2017

honeymooners disease

Another name for a uninary tract infection. More specfically a UTI from too much sexy time.

A women reads too much porny fanfiction and proceeds to have rough intercourse at a higher than normal rate causing her to get honeymooners disease.

by pandabear1975 August 29, 2009

Terminal White Disease (TWD)

Being 100% Caucasian and performing dances like the Donkey Kong or any variety of hip-hop moves. It just doesn't work, no matter how tall you are....

(at a club) "Wow, look at that guy he's suffering from Terminal White Disease (TWD)"

by susieQ1286 March 9, 2011

Adam's Disease

The act of acting like a 'school girl' upon seeing the naked flesh of a women's breast region.

Girl: *naked* Are my boobs too small?
Boy: Eeeeeeeeeeeee~ *jumps up and down*
Girl: You must have Adam's Disease.

"So, what happened?"
"Well Doctor, I lost a liter of blood while staring at my girlfriends boobs."
"Ah, you must have Adam's Disease."

by Kingpoopoo October 14, 2011