A Bison shit Stampede is what results when someone goes to a Buffalo Wild Wings and becomes adventurous with the spicier sauce on the wing menu. Unless equipped with bowels of steel, the result is a rush to the bathroom. Followed by a "stampede" of shit, usually in liquid form.
"John tried the 'wild' sauce. Judging by the screaming coming from the bathroom? He's probably in the middle of a Bison shit Stampede."
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