Tay-Sachs Disease

Tay-Sachs disease is a rare genetic disorder in which an enzyme called hexosaminidase-A is missing. This enzyme is vital in breaking down harmful substances known as lypids. When these lypids build up in the brain they cause brain dammage, and cause death usually by the age of 3 to 5 years of age. Its autozomal recessive so both the wife, and the husband have to be carriers of the Tay-Sachs ghene to have a possibility of having a child affected with Tay-Sachs disease. If both partners are carriers they have a 1-4% chance of having a child affected with Tay-Sachs disease. Tay-Sachs disease is ALWAYS fatal.

When Fred was born genetic tests showed that he had Tay-Sachs disease disease. He died at the age of 3 years.

by ventilator98 April 4, 2009

Mad Snail Disease

When a person is so dumb it frustrates those around him/her

wow that person isn't so smart he/she must have Mad Snail Disease

by TheKingPin17 August 12, 2017

Diseased Rectal Wart

A wart on one's ass that consists of secreting puss, yellow/green liquids, and many vile odors.
ADVISORY: DO NOT TOUCH ONE. YOU WILL DIE.

HOLY CRAP!!111!!!11!1!!1!!11 that guys ass is wet and he smells, he's got some baaaadddd Diseased Rectal Warts.

by Tim :] February 9, 2007

grey goose disease

When a person becomes drowsy from alcohol. Grey Goose is a type of Vodka.

Chamillionaire: If liquor makes him drowsy, he gonna say he got that grey goose disease

by wutzzzzzz June 15, 2008

White Girl Disease

A condition in which any part of the populous, excluding the white girl, starts to act and channel their inner white girl. Familiar symptoms include buying frappucinos from Starbucks and having a Tumblr account. Other symptoms may include constant bitching and or excessive phone usage.

Martha: Rick, I think Becky is coming down with White Girl Disease...

Rick: Get her to the hospital! This shit is deadly Martha!

by Nugpon May 26, 2016

Happy Happy-Not Not Disease

A synonym for bipolar disorder;

A mental health condition defined by periods of extreme, often inappropriate, and sometimes unpredictable mood states.

1. I think Sally suffers from Happy Happy-Not Not Disease--10 minutes ago she was threatening to kill herself, but now she's laughing and having fun.

2. You will contract Happy Happy-Not Not Disease and die.

by malchik_gei March 27, 2007

T-shirt Disease

undershirt is longer than the shirt that is covering it.

Look at Hannah Neugent's ungodly case of T-shirt Disease..

by PG Public Enemy March 17, 2008