Tay-Sachs disease is a rare genetic disorder in which an enzyme called hexosaminidase-A is missing. This enzyme is vital in breaking down harmful substances known as lypids. When these lypids build up in the brain they cause brain dammage, and cause death usually by the age of 3 to 5 years of age. Its autozomal recessive so both the wife, and the husband have to be carriers of the Tay-Sachs ghene to have a possibility of having a child affected with Tay-Sachs disease. If both partners are carriers they have a 1-4% chance of having a child affected with Tay-Sachs disease. Tay-Sachs disease is ALWAYS fatal.
When Fred was born genetic tests showed that he had Tay-Sachs disease disease. He died at the age of 3 years.
by ventilator98 April 04, 2009
wow that person isn't so smart he/she must have Mad Snail Disease
by TheKingPin17 August 12, 2017
A wart on one's ass that consists of secreting puss, yellow/green liquids, and many vile odors.
ADVISORY: DO NOT TOUCH ONE. YOU WILL DIE.
ADVISORY: DO NOT TOUCH ONE. YOU WILL DIE.
HOLY CRAP!!111!!!11!1!!1!!11 that guys ass is wet and he smells, he's got some baaaadddd Diseased Rectal Warts.
by Tim :] February 08, 2007
by wutzzzzzz June 16, 2008
A synonym for bipolar disorder;
A mental health condition defined by periods of extreme, often inappropriate, and sometimes unpredictable mood states.
A mental health condition defined by periods of extreme, often inappropriate, and sometimes unpredictable mood states.
1. I think Sally suffers from Happy Happy-Not Not Disease--10 minutes ago she was threatening to kill herself, but now she's laughing and having fun.
2. You will contract Happy Happy-Not Not Disease and die.
2. You will contract Happy Happy-Not Not Disease and die.
by malchik_gei March 23, 2007
by PG Public Enemy March 17, 2008
A condition in which any part of the populous, excluding the white girl, starts to act and channel their inner white girl. Familiar symptoms include buying frappucinos from Starbucks and having a Tumblr account. Other symptoms may include constant bitching and or excessive phone usage.
Martha: Rick, I think Becky is coming down with White Girl Disease...
Rick: Get her to the hospital! This shit is deadly Martha!
Rick: Get her to the hospital! This shit is deadly Martha!
by Nugpon May 26, 2016