Macaroni Penis Disease

Closely associated with peyronies disease.

Macaroni penis disease most frequently occurs as a side effect from Russian Macaroni

Last week my friend was diagnosed with macaroni penis disease. He thinks he got it from the Russian macaroni party dip.

by Electric Joe August 22, 2018

Ashy Knees Disease

Ashy Knees disease is a "disease" that make your knees look very ashy, usually because they have no moisture such as lotion. Ashy Knees disease can spread everywhere, such as your elbows, ankles, cheeks and nose. Make sure to lotion up before leaving the house, especially during the winter as during that season ashy knees disease is very, very visible.

Friend: "Omg have you heard that Miles has ashy knees disease?"

Me: "I told his dumb self to use lotion everyday! If he listened to me, his knees wouldn't be so ashy!"

by SpookyBlackBabe October 2, 2021

Mitchum-Humsterfumper Disease

Mitchum-Humpsterfumper Disease, whereby a person is completely unable to process or rationalize the existence of eggs or egg byproducts.

Cloefus; Whoa, that bitch just got a plate of poached eggs dumped on her by that clumsy ass waitress, and she ain't doing nothing 'bout it, except stuffing her pie hole... Leroy; Man, that chick prolly has Mitchum-Humsterfumper disease, and she don't care 'bout no eggs running down her forehead! Yo

by Is this your homework, Larry? May 12, 2015

Mad pow disease

When theres so much powder at the ski resort you and your friends are going absolutely crazy running over each other and totally destroy one another.

How was the resort today?
Dude, after waiting in lift line for 2 hours, once we got to the top everybody totally had mad pow disease, it was sick

by leperms December 13, 2014

Tu-Sty Disease

The unfortunate act of loading the toilet paper roll incorrectly, which causes the toilet paper to be dispensed under the roll. Symptoms present are absence of common sense, inability to understand the obvious repercussions of the act, and irascible guests to said home individual resides in. May cause loss of friends, loss of IQ, and loss of bathroom priveledges.

Cause: unknown

Cure: a swift kick to the face

Bro 1: I broke up with my gf today, bro.

Bro2: Bro, why?

Bro 1: she has Tu-Sty Disease, bro. I can’t love someone who could infect me at any second.

Bro 2: oh fuck that, bro. Good choice. Bitches be crazy.

*Bros high five and continue to walk to their dads boathouse in their Patagonia’s, chubbies and boat shoes*

by Stuckonpuck September 9, 2018

motor neuron disease

A "Disease" which is not even a disease. An illness that gradually destroys the motor neurons in your body. Eventually the sufferer wont be able to do anything. The Hollywood actor, David Niven had the "disease". There is no known cause of the illness, nor a cure, but there is research going into the prospect of using stem cells to recreate the savaged motor neurons, but it's not yet known if the disease will destroy the new ones too. Has nothing to do with shakey hands.

My dad had trouble walking, he went to the doctor for tests. He later found out he had motor neuron disease. A while later he got pnumonia and died 3 days after christmas day, and I was 12!

by christ0pherjack December 28, 2005

Chris Ryan Disease

The medical condition when one is so sexually attracted to a black woman that he will throw himself onto her in a sexual rage that cannot be stopped by any force on the face of this god given free land.

Mike: "God dammit wei, i thought i told you to control yourself when we are walking on the street. You always go nuts when a black chick walks by, this is the third time you've taken your cock out and asked her to jack you off like a goddamn baboon."

Wei: "Ahh man come on. I just have that Chris Ryan Disease. It's a medical condition and not my fault. When i see a black girl, this sexual urge comes over me and i can not control myself."

by bridget rowland December 17, 2008