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it's over 

A pronouncement of the termination of a relationship by either one of the two parties involved in said relationship or an outside, objective party.
You: "Things were going so well. I called her twice a day, e-mailed and IM'ed her every five minutes, and gave up all my friends to hang out with her just to show her how much I cared. I honestly don't know what happened."

Vicfan: "It's over."
it's over by vicfan March 23, 2004
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it's over 

1. your relationship
2. your dating situation
you: "i'm so confused"
shonuff: "it's over"
it's over by shonuff March 17, 2004

It's over 

when its the apocalypse for you, like say you submitted something late by one minute
Dude1: Yo, did you print your English hw last night
Dude2: no dude i submitted through email, we were all supposed to
Dude1: It's over, It's all over now
It's over by TOTALLYNEVERGOOD123 September 26, 2019

It's over 

Used to repeat the fact that an incel will never get into a relationship due to unchangeable circumstances.
Truecel: I'm balding at 18 and am only 5'3".

Truecel 2: it's over for you buddy boyo.

Truecel: Never began.
It's over by its0verbuddyboyo April 13, 2023

It's over 

When something is over finished done NOT STARTING AGAIN. A relationship that has gone down the drain....
Girl to a guy: It's over
Guy to girl: What time are we going on a date
Girl to guy: What don't you get about IT'S OVER
It's over by bundlesofjoy December 5, 2011

it's over 

A slang term that used when someone think they have you beat in a game. Usually used when the person believes they have superior skills.
It's over Bob, just give up now.
it's over by DeathHasCome July 24, 2008

It's Over 

When two people are roasting and one person literally melts the other. The crowd shout's "it's over" due to the obliteration that occurred.
Trevor: Boy ur hairline lookin like the McDonald's logo! Ba Da Ba Ba Ba head ass!

The crowd: DAYYYYYMMMMM!!! IT'S OVER BRUH! IT'S OVER
It's Over by xFrqity December 10, 2019