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Depresspacito 

When you're almost depressed but the only thing keeping you from being depressed is the hit song despacito.
"Man, after my favorite hooker, Jephina, died of AIDS I'm feeling really depresspacito today."
Depresspacito by Arjience June 12, 2018

Depressmas 

Man I'm having such a depressmas.
Depressmas by DJJW December 20, 2008

Depressant

depressant

1. A chemical or substance that depresses the nervous system. e.g. alcohol.Often addictive.

2. A person who ruins everyone elses fun.

3. A relationship.

4. A member of the opposite sex.
John-"Hey whats wrong with you Timmy?"

Timmy-"I am full of this depressant," Points to a bottle of cheap vodka, "Because I'm still living with this depressant." points to expensive, unloving woman.

deprestlayer 

Yo deprestlayer what’s poppin
deprestlayer by Deprestlayer October 8, 2020

Depressants 

Ants that help you when you are sad. They may be therapy ants, or just good friend ants. Either way, they are ants. This is not to be confused with the medically prescribed anti depressants. These are just for any person who feels down.
Person 1: I'm feeling sad..
Person 2: Are you okay?
Person 1: yeah.. My depressants will help me.
Depressants by Sockth December 28, 2018

depresstale

An AU created by YouTuber LeoYoshi54321 based around Undertale and being depressed.
I love 'Orange Juice'! ( ͡° ͜ʖ ͡°) Depresstale Papyrus' is great straight from the source!