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An STD or infection of the digestive tract caused by giving one a "rim job" or ingesting fecal matter while performing oral on ones anus.
I had to go get antibiotics for my C diff, the bitch forgot to wipe and now I'm shitting a Hershey factory!
C diff by The Underground Pharmacist February 14, 2018
Related Words
C. diff C.O.W. c c hair C-row C.T. C.S. c u C.R. c notes