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Means "You Only Lotus Once".

Lotus referring to the giant lotuses on Christofer Drew's butt. But of course, Christofer defies the law and lotuses twice.
Hipster Chick: Y.O.L.O!

NSN Fan: Christofer Lotuses twice.

Hipster Chick: The fuck?

NSN Fan: Ugh, just go away.
Y.O.L.O by lovethelotus May 17, 2012
Related Words
Your Only Weird Once

Its another way of saying Y.O.L.O
Boy: Y.O.L.O

Girl: No , its Y.O.W.O
Y.O.W.O by HarmonyLovesYou June 21, 2012
Drake fans: you only live once.
Christofer Drew fans: you only lotus once .c;
Christofer Drew: make fun of my lotuses and ill eff you up .c; Y.O.L.O.
Y.O.L.O. by haiguise May 17, 2012

Y.O.G.M.O 

Acronym for You Only Get Murdered Once.

Pronounciation: |jəɡmoʊ|
1) It is a proper counter-response to those who scream YOLO at very inconvenient and often inappropriate times.

2)exclamation describing negative and often hateful emotions to person who the speaker believes deserves neither happiness nor life.
Man 1: "Look at that bitch. I'm gonna go talk to her! YOLO."
Man 2: Did you really just say YOLO in real life!? Ugh. Y.O.G.M.O
Y.O.G.M.O by Kvaromind July 1, 2012
'sup y.o.b?'
Y.O.B by Mothertruckingbeach August 24, 2016

Y.O.Y.O. 

"Nikki, can you help me with my car? It's not working."
"Nah I can't. Y.O.Y.O. You On Your Own."

"Professor, can we have a study guide for this test?"
"No. Y.O.Y.O. Y'all don't need my help."

"Chrissy, take me back! I'm sorry I cheated on you. I'll be faithful to you again I swear!"
"No Jerry. YOYO. I'm moving on."
Y.O.Y.O. by KookieKuusi February 9, 2017