When an
individual, group of individuals, a thing, or an event epically destroys the good vibe, buzz, or high of every participating member of a large party. A massive multiple killjoy. Often is induced by
the police, people that can't handle their substances, party crashers, and
Justin Bieber.
"We were having the most
outrageous party, but then the cops showed up and it was just a major buzz genocide, man."
"Drew's party was the craziest shit since
Spring Break '98, but then some asshole started playing
Justin Bieber!"