The state of being so horny that it's actually altered one's personality and/or behavior toward others, but not nessessarily in an increased sexual or raunchy demeanor. Others may notice the change and attribute it to depression, stress, or a mild concussion, since most who experience offness display symptoms of being aloof, twitchy, and often have delayed reaction time since their mind is on other things.
Friend #1: Hey, have you noticed Angela's been acting a little weird today?
Friend #2: Oh, don't worry about it, she's just seriously off. I think she's hooking up with Mike this weekend, so she should be fine by Monday.
Derived from the process of censoring songs by playing vulgar words in reverse so the song can be played on the radio or on television.
(The word "f--k" played in reverse sounds like "off").
*Note: It is not pronounced with an "aw" sound such as "Turn the light switch off". The "O" is pronounced as the letter "O".