LMSO 

Acronym, Meaning Laughing my Sh** out.

If you're on a date 'oh Look baby I laughed so hard I sh**'
"LMSO!'

LMSO by P.B.B July 3, 2007

Lmso 

laugh my sack off

Elizabeth: that moment when __ILOVE_ANGEL__ tries to follow you on IG #

Jairo: __I_LOVE_ANGEL_never follows me

Elizabeth: he has a creepy ass profile pic, _I__LOVEANGEL_ IS_ABOUT_TO_GET_BLOCKED

Jairo:Lmsao

Elizabeth: Gio just ate shit

Jairo: Lmso

Lmso by Eli76ohh July 23, 2015

LMSO 

Stands for "laughing my scrotum off"

It is used when you are laughing so hard that you feel like your penis is going to fall off.

"Why did the chicken cross the road? To get to the other side!"

"LMSO"

LMSO by ssiilllly October 22, 2015

Lmso 

Laughing my shit out

Yo remember when I fucked your mom
Yo "Lmso" not cool bro

Lmso by Mela Lica June 18, 2016

LMSO 

Noun:

Laugh my socks off

Zach and i was having a blast watching people slip on ice LMSO.

LMSO by Young Cabe January 16, 2017

LMSO 

Laughing my socks off

Haha, that meme made me LMSO

LMSO by ihatetw April 24, 2017

Lmso 

Laughing my shit out

Her: Girl he lucky I ain’t know he lived with his mama.
Girl: Lmso.... you stupid

Lmso by HdSneakerhead October 4, 2018