Chromosome powerplay 

Meaning you have an extra set of chromosomes. Nice way of calling someone a retard. Powerplay is a man-up scenario in sports, mostly from opposing team serving a penalty.

Person 1: "Wow, that guy is a moron."

Person 2: "Yeah, they must have a chromosome powerplay going on."

Chromosome powerplay by M_Dubz152 June 6, 2023

chromosome thief

(n). One who steals another's chromosomes to bring about autism, down syndrome, etc.

Look out, there's a chromosome thief coming towards us!

chromosome thief by _thememeprophet_ February 27, 2017

extra chromosome 

What makes a Down's Syndrome person how they are.

Timmy has an extra chromosome, that's why he goes to special school.

extra chromosome by Ray Flynn May 20, 2005

sex-chromosome anomaly 

This is a genetic abnormality that does not have to do with being gay, lesbian, etc. This abnormality is seen when the XY or XX chromosomes have more than the usual X and Ys. This can lead to infertility in males or females and physical traits not normally of that sex. For more information, check the page on biology. about. com about Sex Chromosome Abnormalities.

Sex-chromosome anomaly (abnormalities) are a result of chromosome mutations.

sex-chromosome anomaly by Phoebe Jones May 11, 2016

smoke yourself a spare chromosome 

To smoke weed until you're retarded, as Down's Syndrome is cause by the presence of an extra chromosome.

Chich : We finished a quarter ounce between us last night, man. I think I'm still kinda faced.

Chung : Shit son, you don't watch out you'll smoke yourself a spare chromosome.

smoke yourself a spare chromosome by Parhelion February 22, 2009

Sensei chromosome 

That one kid with Down syndrome you grew up with. The one that was sometimes too violent because he didn’t know his strength, but everyone still like him because of his earthly wisdom

Watch out, Sensei chromosome might teach us some new fighting moves

Sensei chromosome by Teamumizoomi March 25, 2020

google chromosome 

A way to reference autism in a more satirical and humorous way.

Thomas: "Ayy man, this nigga spreadin' his google chromosomes around, what we gonna do?"
Ben: "Shut the fuck up Thomas, I'm sick of your bullshit; everyone is."

google chromosome by Scrötumm Teeklurr June 11, 2017