uno 

Uno is a derogatory term for a Mexican.

The uno mowing my lawn fucked up one of my peonies.

uno by bigmike/wan January 13, 2019

Uno 

uno the game that ruins all my friendships

i plus 4 my friend and then he pulled out a reverse card we were never friend again uno

Uno by @evapappano May 16, 2019

Uno 

How to end friendships in 5 seconds

In uno we all stacked +4 and now we all hate eachover

Uno by Universe the madlad December 28, 2020

uno 

pat ogrady a kid in oceanside new york who lives on mout ave. ( beacause he had sugurey on hs balls and the doctor cut his left nut off.

he got kicked in the balls by a kid in fourth grade.

uno by joe polchinski March 23, 2005

UNO 

The end of all friendships

Uno

Guy: I'm sorry
Guy: what do you mean sorry what for
Guy: For this. ( Placed a plus 4)
Guy: I hate you were no longer friends

UNO by Lonely guy 999 August 5, 2018

UNO 

The family ripper and the friendship destroyer

"Billy, I'm sorry but I'm disowning you..."
"Why dad?"
"You choose this path when you played that +4 during UNO"
"I'm sorry"
"It's to late to say sorry Billy"

UNO by •ButterCream• April 26, 2021

Uno 

A game specially made for retarded and drunk people who are desperate to be social but don’t want to make an effort. The game basically requires you to use 2% of your brain cells and is therefore based on pure luck

“ Feras wanna play uno?”
- No i’m gonna go find some new friends, enjoy

Uno by whatupdocc February 2, 2023