ofb 

Obama Fan Base. Used to describe supporters of Barack Obama. Especially those online.

Oh, the OFB is going to really get riled up about that.

ofb by Lulu73 April 5, 2008

OFB 

Noun. acronym for the "Open for Business" sign - as in, eagerly seeking a relationship with the opposite sex. Most typical of single females in their mid to late 20's when their apparent lack of wanting to be alone becomes apparent to the untrained eye.

Dave: "That's weird, Eve just asked if I want to go to lunch on Wednesday. Didn't she just get out of a relationship with Adam?"

Russ: "About a month ago, and I had lunch with her last wednesday. Her OFB is in the window."

OFB by Spike83 August 17, 2008

OFB 

Official Fuck Buddy

Guy or girl who you use for sex only is your OFB

OFB by xoxoK May 12, 2011

OFB 

Obese Fat Bitch

Daityn is such a OFB

OFB by Garrywithorpe June 2, 2018

OFB 

oh fucking balls

OFB I have a test tomorrow that I haven't studied for yet. Im fucked

OFB by hayder9990 July 8, 2011

OFB 

Obssesive Facebook Disorder

you have OFB

OFB by facebookthy May 20, 2009

OFB 

Noun: The acronym OFB stands for the term Old Fake Boobs. It is used to describe implants that were implanted a long time ago, and look very fake. Fake boobs that look like stretched out water balloons. This is commonly seen among frugal, white, female dancers who have PMS and are addicted to alcohol, Xanax and Prozac.

Brian: "Hey Kyle, Lindsay K. is OFB!"
Kyle: "She should have gotten a nose job instead! hahaha"

OFB by Coronas69 June 2, 2013