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in referance the Lil Jon & The East Side Boyz song "Da Blow" where the hook states "the blow, the pills, the yack, the herb". The term "yack" is actually referring to cognac (pronounced: "cone-yack"). So in essence the song is referring to the blow (cocaine), the pills (ecstacy and/or pharmacutical), the yack (cognac), the herb (marijuana). Which covers all the most common methods of getting fucked up.
In less urban environments, the term is more commonly used to describe the act of vomiting.
noun: yack means congac
verb: yack means to vomit
Da blow, da pills, da yack, da herb... (repeat)
or
I drank too much, I think I'm gonna yack.
yack by hunnygrl420 July 26, 2009
verb. Meaning to throw up or vomit.
I am going to yack on your sweater.
yack by ToplessFlamingo January 25, 2007
Abbreviation of Cognac - i.e. expensive Brandy. Alcoholic beverage
yack by Mutspelski February 15, 2005
All that Edward does is talk yack.

Edward: it's kinda like the idea of dog years
you know like a dog is 5, but it's actually like 30 in dog years
there should be some kind of conversion for girls to guys cause you know, girls kind of peak early
so like a 26 year old guy is like an 18 year of girl
Me: SHUT THE YACK UP!

Less yack, more work.
Yack by #.1 August 16, 2010