uppies Share definition Flag when you (as a little baby man) want to be picked up and lifted into the air by another person. Uppies! Uppie, uppie uppie! Hm... No uppie? It's Mr. Worldwide, it's Mr. 305. If you do not give me an uppie, I will piss all over your feet. uppies by monkeysforsale May 4, 2021 0 0 Get merch Get the uppies mug. Buy Now — $32.95 See more merch