UYB 

UYB = Use Your Brain.
usually use for telling friends or jokes.

UYB, badass!!

UYB by Suicideynxxx September 15, 2010

UYB 

Acronym: Up Your Bum/Butt is a safer alternative to femoral injecting for drug users.

While UYB is a safer alternative for injectors it carries greater risks than other non-injecting ways of taking drugs such as smoking, swallowing, or snorting.

Drugs taken UYB have a faster and fuller effect than when smoked.

My groin is pinned to shit, gonna have to go UYB.

UYB by EJO, UK August 1, 2008

uybwac 

Acronym for "up your butt with a coconut"

It sounds kind of stupid when you say it to someone, mostly because they usually don't know what you're talking about and probably think that you're a retard. Once you explain what it means you'll probably get your ass kicked.

Bob - "Uybwac, and wyai (while you're at it) you can gfym (go fuck your mother) yddb (you dirty dooshbag)!"

Johnson - "Igbyamf (I'm gonna beat yo' ass beotch)!"

uybwac by Dr. Todd Fuquad PhD March 18, 2007

UYBM 

Unarmed Young Black Male

What happened downtown last night? There were police everywhere!!! Well, another UYBM was shot when he got pulled over for a burned out taillight.

UYBM by Wyatt Ever March 6, 2019