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Used in messaging or email to communicate surprise or exasperation beyond that which would warrant a simple "OMG". Abbreviation of "Oh My God, Meredith!", an exclamation used (frequently) by contestant Gretchen on Season 7 of The Amazing Race. The "Meredith" named in the phrase is Gretchen's husband and race partner ... Meredith.
OMGM! We don't have any milk, so I had to have water on my corn flakes AGAIN!
OMGM by WurstEver March 1, 2009
Related Words
An acronym that refers to the phrase uttered by Britney Spears during a concert in Tampa on March 9th, 2009. Apparently, she had a wardrobe malfunction and didn't realize her mic was still on. After the song ended and the lights dimmed, she exclaimed, "My pussy's hanging out!" Even though, "Oh my god" was not said, omg prefixes the acronym to signal that it is purely netspeak and should not be used outside of the the intrawebz.
Britney Spears: OMGMPHO!!1!

Admiral Ackbar: It's a flap!
omgmpho by Fiddle Stix December 17, 2009
Abbreviation for "Oh my God, My Vagina."

This expression is used when a woman hears/sees something so arousing that she is overcome by sexual desire.
"Did you see that video of Eli Roth speaking French?"
"OMGMV"
OMGMV by yocheck October 7, 2009
Oh My God My One….
OMGMO! My One Chance to sleep with Elisa and I blew it.
OMGMO by TWSD March 15, 2022

omgmissile 

When you're playing a war game, and you suddenly are hit, it is common to say "omgmissile". This became adapted just to be said in general online chat, and is often shortened to omgmsl, which is mistaken for omgmisled.
John: omgmissile, I wus hit!
Paul: omgmsl, UR such a 'tard..
omgmissile by sugarrmouse October 18, 2008

OMGMMISAB 

daughter: Can I go out my boyfriend tonight?
mother: NO can do!
daughter (to boyfriend): OMGMMISAB!
OMGMMISAB by daebello August 31, 2010