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A blonde haired girl who squishes ants for a living. She's also known for smashing purple-haired-gremlin's balls. She'll bully you if you're a introvert nurse, so watch out.
Person 1: Woah she's pretty
Person 2: Bro watch out she's a Hiyoko
Person 1: Right I'll watch out
Hiyoko by ashleytheanimeweeb June 8, 2021
Hiyoko is best girl friend m dr2

Extremely underrated and mainly hated by Mikan stans
"Have you heard about Hiyoko"?
"Yes, she's best girl".
Hiyoko by H1y0k0 June 25, 2021
Hiyoko is a bratty bitch who squishes ants and bullies people for a living. You have a bigger chance of her bullying you if you are a nurse.
Hiyoko by _sceneibuki June 22, 2020

Hiyoko Saionji 

best dr2 girl who deserved better and who had a lot of potential for character development but the ultimate nurse said no.
Hiyoko Saionji haters are just jealous because they didn't get to shower with mahiru
Hiyoko Saionji by koreandaaa May 13, 2021

Hiyoko Saionji 

A little bitch that's like 4'9. She appears in Super Danganronpa 2. She bullies people who are weaker than her, just so she can boost her ego.
Person 1: "Can you stop acting like Hiyoko Saionji please?"
Person 2: "No, you nasty roach!"
Hiyoko Saionji by swaggyyuri March 14, 2021

mamaie_hiyoko 

A lesbian girlboss who loves Jean and being horny. No she actually likes Jean. More than she probably should. She loves Jean way too much. Oh she’s a hardcore Eimiko shipper. :DDD
-Coaie ce plm e #jeansolos??
-Un hastag creat de mamaie_hiyoko pentru ca e gay si obsedata de Jean.
-Frumos....