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A transphobic slur. Like the n-word for transgender people (People whose sex misaligns with their gender.)
Keith: Your ‘girlfriend’ is a dude, total trannie
Victor: Dude, that’s transphobic! My girl is a girl, dawg. And anyway, you’re cis; you can’t say that word.
Trannie by Smol Trans Girl November 29, 2020
Some Ugly Guy: Dude, that chick has a penis...she's a Trannie.

Another Ugly Guy, with an afro: How the hell would you know!?


::They both get into a fight::
Trannie by Hank Tanks on Crank June 28, 2004
Someone who was born with both balls and vagina. I have male and female parts. I dont find this to joke about. I have kept this secret a long time and now im comfortable with it.
I have male and female parts and im proud of it. Trannie life.
trannie by ihjs September 18, 2007
A name for a person born on the wrong gender
Paris Hilton is obviously a trannie.
trannie by Astin Powers July 25, 2008
Trannie is someone with a mental illness that makes them think they are the wrong gender.
Male: I am a girl
Male 2: You are not, trannie
Trannie by TranniesSeething September 9, 2021
A person who is called Annie and is trans
Annie is a trannie
trannie by Gneil4bl4ck August 12, 2019