lo-fro Share definition Flag Poorly-groomed pubic hair. (ie. "low 'fro") An afro down below. You gotta take care of yourself. No one wants to go down on a lo-fro, yo. lo-fro by Mandy S. June 22, 2005 0 0 Get merch Get the lo-fro mug. Buy Now — $32.95 See more merch