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Stands for "Fuck That Shit Homie" it is the best advice ever given to Pete Davidson by Colson Baker aka Machine Gun Kelly. This line was originally said in "How we met: Pete Davidson and Colson Baker" interview from 2019. By these words was Pete advised to not take difficult situations or people seriously and let it to figure it out by it's self. It is synonymous to "It is what it is". FTSH was popularized in Eastern Europe by Valery and Elena whom get a couple tattoo of letters "FTSH " to remind them of their friendship, roots of their friendship and not giving a fuck about non-pleasing things in life. It really became a life motto.
V: "Robert F. said behind my back that I'm a slut."
E: "FTSH"
V: "But he hurt my feelings and I cried to Kissland by the Weeknd"

E:"Fuck That Shit Homie, fuck him, you're litteral queen and he's just jealous that you're too good for him. He's a pussyless sad man."
FTSH by FuneralBreadProduction December 2, 2021
Related Words
ftsoh ftso ftsch FTIOH FTSH ftsoc FTSOF Ftsofh ftsofuiudsfkpwm ftsom
For the sake of fuck.

FFS = "for fuck's sake", NOT "for fuck sake".

And, "for fuck's sake" = "for the sake of fuck". Just as "for Pete's sake" = "for the sake of Pete", or "for goodness' sake" = "for the sake of goodness".
FTSOF by The Spelling Fairy October 23, 2009
I want you to ftsom
ftsom by babykins February 23, 2015
fuck the shit off; the last resort of the acronyms when dealing with utter plebs
pleb69: ur mom is so ghey
jeliza: ftso
ftso by JelizaRose March 9, 2008
ftsch by Mr. GeiLSten December 12, 2010