Not literally a pain in one's
anus or
gluteus maximus, though either would count.
Something quite annoying, but not as bad as a
ballache, which would also be expected to last longer.
People, Places, Things: it doesn't matter. Often shortened to just: a pain.
Was that your
uncle?
Yeah. What a pain in the arse.
Well, i wasn't gonna say anythin, but...
You wanna meet my
Dad! What a
ballache.
Shit, he's coming over, time for
a cool sharp one.