Futuristic curse, synonym for "goddamn." (Created by Joss Whedon for _Firefly_ TV series)
Bones: "Damn it, Jim. I'm a doctor, not a goram doorstop."
A combination of "bastard" and "son of a bitch."
Neek: Sorry, guys. I just ate the last Timbit.
Tok: Fuckin' bastich.