CognitiveFuel's definitions
Thiophene is a chemical that is useful in a lot of stuff. It can be bought or synthesized from butane and sulfer at the vapor phase at 65 °C. Thiophene is an aromatic compound. Thiophene can be chloromethylated by formaldehyde solution and hydrogen chloride at 5 °C or lower to 2-chloromethylthiophene/2-(Chloromethyl)thiophene (TP-MeCl).
Properties
Chemical formula
C4H4S
Molar mass
84.14 g/mol
Appearance
colorless liquid
Density
1.051 g/mL, liquid
Melting point
−38 °C (−36 °F; 235 K)
Boiling point
84 °C (183 °F; 357 K)
Magnetic susceptibility (χ)
-57.38·10−6 cm3/mol
Refractive index (nD)
1.5287
Viscosity
0.8712 cP at 0.2 °C
0.6432 cP at 22.4 °C
Properties
Chemical formula
C4H4S
Molar mass
84.14 g/mol
Appearance
colorless liquid
Density
1.051 g/mL, liquid
Melting point
−38 °C (−36 °F; 235 K)
Boiling point
84 °C (183 °F; 357 K)
Magnetic susceptibility (χ)
-57.38·10−6 cm3/mol
Refractive index (nD)
1.5287
Viscosity
0.8712 cP at 0.2 °C
0.6432 cP at 22.4 °C
Tony: I synthesized 2-chloromethylthiophene from thiophene.
by CognitiveFuel September 11, 2023
Get the Thiophene mug.4,4'-Difluorobenzophenone (4,4-Difluorobenzophenone; 4 4-Difluorobenzophenone; 4 4'-Difluorobenzophenone) is an intermediate in the synthesis of the polymer PEEK and is also used in the synthesis of Flodafinil (Flmodafinil, Difluoromodafinil), Fladrafinil (Difluoroadrafinil) and Modafiendz (N-Methyl-Flodafinil, N-Methyl-Flmodafinil).
Tony: I synthesized Flodafinil (Flmodafinil) by using 4,4'-Difluorobenzophenone and sodium borohydride in ethanol, then converting the 4,4'-(Difluorophenyl)methanol to 4,4'-(Difluorophenyl)methyl bromide using Hydrobromic acid and Zinc chloride catalyst. Then reacting it with sodium thioglycolate. Then a few more steps and I got Flodafinil.
by CognitiveFuel September 11, 2023
Get the 4,4'-Difluorobenzophenone mug.2-Iodothiophene (TP-I, Thiopheyl iodide, 2-ThioPhenyl iodide) is used as an intermediate in the synthesis of TP2P (ThioPhenyl-2-Propanone, 2-Thienylacetone). 2-Iodothiophene can react with ethyl acetoacetate and sodium ethoxide using CuI (Copper Iodide) and then reacted with hydrochloric acid and heated. 2-Iodothiophene can also undergo grignard reactions to obtain TP2Pol (ThioPhenyl-2-Propanonl, 2-Thienylisopropanol).
2-Iodothiophene has been obtained by addition of half of 50% aqueous nitric acid dropwise to a mixture of iodine and thiophene with vigorous stirring. As soon as the evolution of gases subsided the rest of the aqueous nitric acid was added to the reaction mixture and refluxed for 30 min. The organic layer was separated and steam distilled to obtain 2-iodothiophene.
Iodination of thiophene with iodine and mercuric oxide at 0°C gave a mixture of 2-iodothiophene (70%) and 2,5-diiodothiophene. 2-Iodothiophene has been exclusively obtained by nitrating thiophene with a mixture of iodine and nitric acid at 90°C. An easy approach for iodination of thiophene is the reaction of iodine with lithiated thiophene.
2-Iodothiophene has been obtained by addition of half of 50% aqueous nitric acid dropwise to a mixture of iodine and thiophene with vigorous stirring. As soon as the evolution of gases subsided the rest of the aqueous nitric acid was added to the reaction mixture and refluxed for 30 min. The organic layer was separated and steam distilled to obtain 2-iodothiophene.
Iodination of thiophene with iodine and mercuric oxide at 0°C gave a mixture of 2-iodothiophene (70%) and 2,5-diiodothiophene. 2-Iodothiophene has been exclusively obtained by nitrating thiophene with a mixture of iodine and nitric acid at 90°C. An easy approach for iodination of thiophene is the reaction of iodine with lithiated thiophene.
Tony: I iodinated thiophene using nitric acid and slowly added it, then refluxed it for 30 minutes at 90 °C. I obtained 2-Iodothiophene.
by CognitiveFuel September 11, 2023
Get the 2-Iodothiophene mug.A eugeroic is a type of drug that acts as a smart drug and is useful for ADHD, Narcolepsy, Phase Sleep Disorder, and helps you remember if you are forgetful. Eugeroics work by mildly increasing dopamine, and increasing histamine in the brain. The dopamine gives you a mild energy boost while the histamine is responsible for wakefulness. Eugeroics are wakefulness enhancers and are different from stimulants since stimulants tend to be addictive and eugeroics aren't very addictive at all. Eugeroics leave you with casual wakefulness and feels like a good night's sleep, while stimulants leave you feeling very hyper.
Examples of eugeroics are: Adrafinil, Modafinil, Armodafinil, Hydrafinil, Flodafinil (Flmodafinil, Difluoromodafinil), Fladrafinil (Difluoroadrafinil), Modafiendz (N-Methyl-Flodafinil, N-Methyl-Flmodafinil, N-Methyl-Difluoromodafinil), and N-Methyl-Modafinil.
by CognitiveFuel September 12, 2023
Get the Eugeroics mug.P2Pol is Phenyl-2-Propanol. It has a floral fragrance and is used in perfumery and in synthesis of chemicals and pharmaceuticals.
Tony: I just oxidized P2Pol to P2P. Then I reacted P2P with ethylamine and formed P2P ethylimine (Phenyl-2-Propanone ethylimine) and used reductive amination in ethanol water (hydrogen oxide) solution with Aluminum Galinstan to yield Ethylamphetamine.
by CognitiveFuel September 16, 2023
Get the P2Pol mug.CHX-Br is short for cyclohexyl bromide (or CycloHeXyl Bromide). Cyclohexyl bromide can react with sodium ethoxide (NaOEt) and ethyl acetoacetate (EAA) to form Ethyl 2-cyclohexyl-3-oxobutanoate. Then react with hydrochloric acid to get 2-cyclohexyl-3-oxobutanoic acid. Heating it up will get you Cyclohexyl-2-Propanone (CHX2P, Cyclohyxylacetone) , a useful intermediate in the synthesis of Propylhexedrine, and carbon dioxide as a side product. Propylhexedrine is good orally in doses of 60mg to 180mg+ to decongest the nose, as a pre-workout, and to lose weight. Cyclohexyl bromide can also undergo other chemical reactions such as turning it into Cyclohexyl magnesium bromide and reacting it with Propyl chloride to get 1-cyclohexylpropane (unless there's rearrangement to 2-cyclohexylpropane).
by CognitiveFuel July 7, 2023
Get the CHX-Br mug.Propylhexedrine HCl is the HCl (Hydrochloride) salt of Propylhexedrine. While freebase Propylhexedrine is a liquid, Propylhexedrine HCl is a solid white salt. Propylhexedrine is made by dissolving it in ethanol and bubbling HCl gas through it. Propylhexedrine is good as a pre-workout, to unclog the nose, and to reduce hunger for weight loss. It is 1/4 the strength of amphetamine, and releases dopamine, norepinephrine, adrenaline (causes vasocontriction), and serotonin. It activates TAAR1 receptors. The dose range is 60mg to 250mg+. Doses of 60mg to 180mg will give you energy, concentration, an urge to lift things and run a lot (adrenaline rush), and more. Doses of 250mg or higher will lead to a buzz (mild to moderate mood boost) to a high (high mood boost), an even greater adrenaline rush, and increased side effects such as anxiety in most, fatigue, anger in some, insomnia, sweating, headaches in some, and more. Stacking Propylhexedrine with CBD and 7,8-Dihydroxyflavone (Tropoflavin) prevents some side effects.
Fernando: I tried 250mg of Propylhexedrine HCl measured in a scale and dissolved in juice and was high for hours. I had the best workout ever for 3 straight hours.
by CognitiveFuel July 7, 2023
Get the Propylhexedrine HCl mug.