A disease afflicting lesbians. A lesbian acquires penis disease when she has sex with a guy and then tries to get with a girl again, normally resulting in rejection.
Heather: "Hey Amanda, you busy later tonight?"
Amanda: "Haven't you been sleeping with Alex? No thanks, I don't want to catch your penis disease."
Amanda: "Haven't you been sleeping with Alex? No thanks, I don't want to catch your penis disease."
by RuggerLez09 June 7, 2011
Penis Disease Syndrome is a disease that infects many males which gives them a penis which can be both good and bad, there are also cases of it being Fatal Penis Disease Syndrome which makes your penis extremely long
by GenerousWombat83 June 3, 2020
Itchy penis disease is a severe thing that happens whenever you dip your ding a ling in melted chocolate and then put it in a Bootyhole that has been coated extra thick with peanutbutter. Then the girl eats the peanutbutter and chocolate off of you.
by Bloody nutsacks April 26, 2020
Closely associated with peyronies disease.
Macaroni penis disease most frequently occurs as a side effect from Russian Macaroni
Macaroni penis disease most frequently occurs as a side effect from Russian Macaroni
Last week my friend was diagnosed with macaroni penis disease. He thinks he got it from the Russian macaroni party dip.
by Electric Joe August 23, 2018
Penis in Mouth Disease(PMD) is often caught by homosexuals and other promiscuous beings. It happens by being exposed to the male reproductive organ too often. After many years of exposure, there is no stopping the need for penis in ones mouth. This is the point of no return. If caught early, it can be treated.
Example 1: Ayy bro, you know that Sarah chick? Yeah, just found out last night she's got the Penis in Mouth Disease. My cocks gonna be limp for days now.
Example 2: So I was at the bar and some dude asked me if I wanted a BJ. I'm like, I'm not into that kind of stuff. It didn't stop him. I later found out he's had Penis in Mouth Disease for 13 years now.
Example 2: So I was at the bar and some dude asked me if I wanted a BJ. I'm like, I'm not into that kind of stuff. It didn't stop him. I later found out he's had Penis in Mouth Disease for 13 years now.
by roflcopters2 July 5, 2009