Top Definition
A polite term for the symptoms of benzine poisoning. This may include explosive diarrhea to the point requiring a shower. May also result in chocolate rain.
You know, if I had the option to separate Mountain Dew and the Syndrome, I'm not sure I would.
by Apalled. March 27, 2009
A word used to describe a hyper, A.D.D., six-year-old-like behaviour.

Can be shortened to the word "syns."
That kid watching Pokemon is so syndrome.

Your little brother is so syndrome, he tried to stab me with a plastic Power Ranger sword.

Tell your syndrome friend to stop breaking things in my room.

He is so syns.
by Harrison Ziv July 18, 2006
noun. A person with unlikeable social peculiarities that prevents most people from developing a close relationship with him or her.

A person who is the embodiment of unlikeable qualities.
I have known my brother-in-law for over eight years and I still can't like him. He is a syndrome.
by koozagar July 28, 2011
A case of medical symptoms linked with a disease and/or special case needs.
Mike: I'm tired

Cook: You have a syndrome
by ii ImBa_S1L3NC3R_Ch4Mp10N x May 22, 2016
The idiot villain from The Incredibles who really should have fought more.
I would have loved to see Mr. Incredible go Bruce Lee/Jet Li/Jackie Chan all up in Syndrome's ass.
by Marcus Reed August 20, 2006
One of the greatest movie villains ever.
When I get too old I'll sell my inventions so that everyone can be super. And when everyone's super... no one will be.
by ChestnutChewer December 05, 2004
That intense feeling of paranoia that you suffer when you're not sure where you stand with a girl you like
ted> dude i really like this chick and it's really eating me up inside
dave> dude you've got syndrome man
by zeocrash April 20, 2005
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