To have sexual intercourse, specifically penile penetration of a soft tissue orafice. Originated with the internet slang term p33n and worked its way into speech through overuse by internet geeks.
A hardo is a person who tries extremely hard at everything. Most times a hardo will try very hard at things that do not require excessive effort. For example, sports practices, gym class, etc.
Wow did you see Jack at practice today? What a hardo!