look up any word:
1. motherfucked
To be severely fucked, used especially when describing the state of a device, piece of software, location, establishment, or a situation.
I think my laptop is motherfucked.

The IRCd: it's motherfucked.

This hotel is motherfucked. There's a dead hooker in the bathtub and I'm pretty sure I saw some bedbugs.

Spidy it's motherfucked.
2. motherfucked
To strongly curse someone for actions one finds unsatisfactory, inapropriate, or rude.
Rick motherfucked Dale for not doing the paperwork.
3. motherfucked
Much like the term fucked, this implies being screwed, in that shit is about to hit the fan for you. Motherfucked implies that the situation is far more grave.
"Oh man, Jimmy owes Johnny 400 bucks and isn't gonna pay it back"

"JIMMY IS MOTHERFUCKED"
by Virtue Jul 6, 2005 add a video
4. Motherfucked
When someone royally fucks you over or vice versa
1. Rick: "Johnnys ex-girlfriend not only knocked his bike over, but she cut both the tires!" Dale: "Damn! she sure motherfucked him!"
rss and gcal