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1.
bone in the face - the one that your chin is attached to; lower jaw
dude... I smashed his mandible!
by Bocaj Esuorps October 25, 2006
 
2.
a mannish jawline found on a woman
Dude, Reese Witherspoon is kinda cute I guess, but I can't get past that MANdible.
by Pahn August 09, 2009