Top Definition
A drug originating from a muffin; has the tendency to make people laugh at 12 am!

Zeev ate a muffin and tried to spell it.... thus the maffine was created!
ThruBluEyes: maffine
ThruBluEyes: hahahhahah

Notice how maffine everything funny, its a good thing :)
by Its12amOnaSundayNight October 03, 2004

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